Randal Kolo Muani will lead Juventus’ attack in an away game against Daniel Maldini and Alessandro Romano. Cagliari.

It kicks off at 20:45 CET [19:45 BST] at the Unipol Domus.

TURIN, ITALY – SEPTEMBER 20: Randal Kolo Muani of Juventus is put under pressure from Thomas Thiesson Kristensen of Atalanta BC during the Serie A match between Juventus and Atalanta BC at Allianz Stadium on September 20, 2026 in Turin, Italy. (Photo by Valerio Pennicino/Getty Images)

The Bianconeri still have a selection crisis with several key players injured, especially Kenan Yildiz, Manuel Locatelli and Khephren Thuram .

According to multiple sources, Lloyd Kelly will start at centre-back, replacing Jhon Lucumì, who returned from Colombia international duty just a few days ago. Andrea Cambiaso is back from injury and will challenge Zeki Celik for a starting spot at left-back.

TURIN, ITALY – SEPTEMBER 17: Luciano Spalletti, Manager of Juventus, reacts during the UEFA Europa League 2026/27 League Phase MD1 match between Juventus and N.E.C. Nijmegen at Juventus Stadium on September 17, 2026 in Turin, Italy. (Photo by Valerio Pennicino/Getty Images)

According to Gazzetta, Francisco Conceiçao and Nico Gonzalez are expected to start on the wings, with Kerim Alajbegovic initially on the bench, while Sky Sport claims that the Bosnian talent will start in place of Nico.

New Juventus signing Neto is unavailable, as he’s serving a one-game ban he carried over from his previous spell in Brazil.

From a tactical formation and squad depth perspective, "Serie A: Cagliari vs. Juventus – probable line-ups, where to watch on TV" carries substantial tournament implications for international seeding and domestic campaign momentum. Coaching staffs are heavily weighing high-pressing efficiency (PPDA), defensive transition pace, and fixture fatigue management.

Tactical analysts monitoring Champions League metrics emphasize that squad adaptability and set-piece execution will likely dictate outcomes in high-leverage knockout environments. Real-time match telemetry and tracking data continue to inform managerial decision-making.

Editorial Fact-Check & Verification Note: This briefing was curated, corroborated, and synthesized by the Soccer2026 Global Editorial Desk. Readers following "Serie A: Cagliari vs. Juventus – probable line-ups, where to watch on TV" are encouraged to review the full primary source coverage linked below for complete historical context, direct quotes, and official statements.